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Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy

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Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy Empty Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy

Post by microbehunter 26/10/2016, 4:01 pm

Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications by Andrea Bonetti, Roberto Leone, Franco Muggia, Stephen B. Howell
2008 | ISBN: 1603274588, 1493957104 | PDF


Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen that produces high cure rates in even advanced nonseminomatous germ-cell cancers, and is widely used in the treatment of ovarian cancers and other gynecologic cancers, head and neck, and numerous other tumor types.

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