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Resistance of Cancer Cells to CTL-Mediated Immunotherapy

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MEDICAL LITERATURES AND UNIVERSITY PASSWORDS :: Medical E-books Departments :: Oncology & Radiotherapy

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Resistance of Cancer Cells to CTL-Mediated Immunotherapy Empty Resistance of Cancer Cells to CTL-Mediated Immunotherapy

Post by qwerty99 8/11/2017, 2:54 pm

Resistance of Cancer Cells to CTL-Mediated Immunotherapy

353 pages
Publisher: Springer; (2015)
ISBN-10: 3319178067
ISBN-13: 978-3319178066
PDF 6.7 Mb

This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

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Resistance of Cancer Cells to CTL-Mediated Immunotherapy Empty Re: Resistance of Cancer Cells to CTL-Mediated Immunotherapy

Post by YLF2013 10/1/2019, 7:49 am

reat
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Resistance of Cancer Cells to CTL-Mediated Immunotherapy Empty Re: Resistance of Cancer Cells to CTL-Mediated Immunotherapy

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Resistance of Cancer Cells to CTL-Mediated Immunotherapy Empty Re: Resistance of Cancer Cells to CTL-Mediated Immunotherapy

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MEDICAL LITERATURES AND UNIVERSITY PASSWORDS :: Medical E-books Departments :: Oncology & Radiotherapy

 
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