Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents

Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents
PUBLICATION DATE: 2016
ISBN: 9783319278810
Edited by: Michael W. Jann , Edited by  Lawrence J. Cohen , Edited by  Scott R. Penzak
Publisher: Springer
PDF 5.9 Mb

This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information for clinicians, students, researchers, and members of the pharmaceutical industry alike.

The first section provides the foundational principles of these drugs.
The second section describes the characteristics of specific agents, nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states.
The third section focuses on drug-drug interactions.

The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology. Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions, is frequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult.

This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.

Includes bibliographical references and index.

CONTENTS

Section 1. General Pharmacokinetic and Pharmacodynamic Principles of Psychopharmacological Agents
1. Pharmacokinetic Properties
2. Pharmacodynamic Properties
3. PET Scan and Other Biomarkers
4. Population Pharmacokinetics
5. Drug Transporters (esp. Blood Brain Barrier)
6. Pharmacogenomics

Section 2. Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Drug Classes
7. Antipsychotics
oral typical agents, oral atypical agents, and long-acting injectable (LAI) antipsychotics
8. Mood Stabilizers
9. Antidepressants
tricyclics, selective serotonergic reuptake inhibitors, serotonergic noradrenergic reuptake inhibitors, monoamine oxidase inhibitors, and other antidepressants
10. Benzodiazepines and Other Sedative Hypnotics/Anxiolytics
11. Opioid Analgesics
12. Stimulants and Other Non-Stimulants for ADHD
13. Cholinesterase Inhibitors and Other Antidementa Agents
14. Anti-Addiction Agents
15. Anesthetics

Section 3. Clinically Significant Drug Interactions With Psychopharmacological Agents
16. Antipsychotics
17. Mood Stabilizers
18. Antidepressants
19. Benzodiazepines and Other Sedative Hypnotics/Anxiolytics
20. Opioid Analgesics
21. Stimulants and Other Non-Stimulants for ADHD
22. Cholinesterase Inhibitors and Other Antidementa Agents
23. Anti-Addiction Agents
24. Anesthetics.

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